"Do you believe in God?"
I think the question of God is a very funny question, but to most it is such a serious subject they don't seem to understand it in my context. You have to re-phrase the question back to them:
"Do I believe in an omnipotent, omniscient entity that created the world five thousand years ago, that created people in his image, that demands the worship of and closely watches over all seven billion people, all the while adding to his naughty and nice list to determine who will gain entry into his eternal club upon their death? That God?"
"Too literal? Then do I believe everything we see/touch/feel/hear/taste was purposely created by one all powerful entity who should be revered for giving us the gift of life? That God?"
Either way, I would have to say no. An emphatic no.
It also works for meaninglessness.
"How could you believe your life has no meaning?"
"How could you believe, as one speck of a person among billions on this speck of dust circling one of billions of stars in this galaxy, which is one of billions of galaxies in the known universe, that your life does have meaning?"